Antioxidant, Blood Booster and Cell Detoxifer
I am excited to announce the creation of the
first natural water-based oral glutathione from avocados. This article will tell
you why this is so important to your health and well-being.
Glutathione (pronounced gloota-thigh-own ) is the body s essential health ABC s
- Antioxidant, Blood Booster and Cell Detoxifer.
It is a tripeptide composed of glutamic, cysteine and glycine. Glutathione is
found in all cells in the body, including the bile, the epithelial lining fluid
of the lungs, and - at much smaller concentrations - in the blood.
Glutathione is the smallest intracellular non-protein thiol (molecule containing
an S_H or sulfhydryl group) molecule in the cells. This characteristic
emphasizes its potent antioxidant action and supports a multifaceted thiol
exchange system, which regulates cell activity.
This small protein, produced naturally in the body, maintains these three
crucial protective functions. In fact, your life depends on glutathione. Without
it, your cells would disintegrate from unrestrained oxidation, your body would
have little resistance to metabolic acids, and your liver would shrivel up from
the eventual accumulation of acidic toxins.
Glutathione is not yet a household word. Even some medical and holistic doctors
who have heard the term may still have only a vague idea of what it is. However,
everyone will soon be talking about this critical non-nutritive substance.
There was a time when only scientists had heard of cholesterol and vitamins, but
today, everyone knows about them. Now the magnificence of glutathione is
becoming known.
In the last five years, over 25,000 medical articles about this substance have
been published, and the scientific understanding of glutathione is gradually
becoming common knowledge.
Each and every cell in the body is responsible for its own supply of glutathione
and must have the necessary raw materials in order to produce it. Glutathione is
always in great demand and is rapidly consumed when we experience any sort of
emotional or physical stress, fatigue and even moderate exercise.
Some well-known causes of glutathione depletion are as follows:
1) Acidic lifestyle and diet
2) Air and Water pollution
3) Prescription and recreational drugs
4) Ultraviolet and Radiation from cells phones, computers, electrical cars,
power lines, hair dryers, etc.
5) Emotional and physical stress
6) Injury, trauma or burns
7) Heavy metals
8) Cigarette smoke
9) Household chemicals
10) Acetaminophen poisoning
11) Exhaust from motor vehicles
12) Septic shock
All of these above factors lead to a build up of acidic toxins that cause the
loss of glutathione as a non-nutritive buffer leading to cellular aging, dis-ease
and finally death.
Why is Glutathione Essential to Health?
Glutathione s three major roles in the body are summarized by the letters A-B-C.
- Anti-oxidant
- Blood Booster
- Cell Detoxifier
These are the three critical processes driven by glutathione.
The Master Antioxidant
Over the past thirty years, researchers have explored the role of antioxidants
in good health as well as the treatment and prevention of diseases involving
oxidation or fermentation by metabolic acids.
Well known and widely used antioxidants such as vitamin A, vitamin E and
selenium neutralize acid. They occur naturally in nature, but not in the body.
They must be introduced as part of a balanced diet.
Given the critical role of antioxidants in good health, it is not surprising
that the body itself manufactures its own natural antioxidants. The most
important of these is glutathione. Because all other antioxidants depend upon
the presence of glutathione to function properly, scientists call it the master
antioxidant.
Glutathione binds to toxins, forming a water-soluble complex - which is
ultimately excreted in the urine or bile as waste.
Food for the Blood
Elevated glutathione levels enable the body to produce more white blood cells.
White blood cells are the body s garbage collectors and are the most important
cells for maintaining sterility of the body fluids.
Glutathione plays a central role in the proper function of the white blood
cells. Dr. Bustavo Bounous, a leading glutathione expert, says, The limiting
factor in the proper activity of our lymphocytes (the white blood cells) is the
availability of glutathione. In other words, healthy growth and activity of the
white blood cells depends upon glutathione s availability. Put simply,
glutathione is food for the white blood cells.
Cellular Detoxifier
Whether we know it or not, we are continually inhaling and ingesting natural and
synthetic acidic toxins. They are unavoidable in these modern times both in our
polluted cities and our poorly engineered food supplies. When the body has the
health and the nourishment it needs, it works tirelessly to eliminate acidic
toxins and to protect itself.
But, increasing levels of environmental pollution are depleting the body s store
of glutathione more and more rapidly.
Our main organ of detoxification of acidic waste products is the lymphatic
system and the liver. This is the body s most concentrated source of
glutathione.
Studies show that low glutathione levels lead to poor lymphatic and liver
function, causing more and more acidic toxins to circulate through the body and
resulting in damage to individual cells and organs.
Medical doctors today routinely use glutathione- promoting drugs to detoxify
victims of certain types of drug overdose.
Glutathione in Natural Medicine
Practitioners of complementary and alternative medicine (CAM) have long
advocated the use of milk thistle for liver problems. It turns out that this
herb works by modestly elevating glutathione levels. The mineral selenium also
produces subtle elevations in glutathione by becoming integrated into the
glutathione peroxidase.
Glutathione in Traditional Medicine
Emergency medical doctors, toxicologists and lung and liver specialists are well
acquainted with glutathione s therapeutic uses. American physicians seeking ways
to raise a patient s glutathione levels can open the standard Physician s Desk
Reference (PDR) and find two options - the pharmaceutical drugs sold under the
names Parlodex and Mucomyst, and the natural dietary supplement found in natural
foods stores derived from whey protein isolate.
Drugs That Raise Glutathione Levels
Pharmaceutical drugs like Procysteine, OTC, OTX, Glutathione monoesters and
Glutathione diesters have been used to raise glutathione levels. However, they
all produce side effects and are unsuitable for long term use.
This pharmaceutical non-nutritive chemical is used to break up mucus in lung dis-eases
such as cystic fibrosis, chronic bronchitis and asthma. It remains the standard
treatment for acetaminophen overdose.
Glutathione in Health and Dis-Ease
It is believed that glutathione has an important role to play in the prevention
and treatment of dis-ease. It may in the future be considered as important to
health as an alkaline diet, exercise and alkaline lifestyle. Clinical tests show
that raised glutathione levels may address some of the eight major health issues
of our time:
1) Cardiovascular
- Prevents heart dis-ease - Shimizu H, Kiyohara Y, Kitazono T, Kubo M, Ibayashi
S, Fufishima M, Lida M. Relationship Between Plasma Glutathione Levels and
Cardiovascular Disease in a Defined Population: The Hisyama Study. Stroke. 2004
Sep; 35(9):2072-7.
- Prevents stroke - Paterson PG, Juurlink BH. Nutritional Regulation of
Glutathione in Stroke. Neurtox Res. 1999 Dec; 1(2): 99-112.
- Prevents atherosclerosis - Coppola L, Grassia A, Giunta R. Glutathione
Improves Hemostatic and Hemorrheological Parameters in Atherosclerotic Subject.
Drugs Exp. Clin Res 1992 18:493-98
- Reverses artherosclerosis
- Prevents reperfusion injury
2) Cancer
Cancer causing polychlorinated biphenyls (PCBs) have been found to alter levels
of glutathione compounds in experiments, which may alter the body s resistance
to certain types of cancer.
Glutathione deficiencies have been linked to many forms of cancer.
- Prevents cancerous tissue
- Suppresses tumor growth
- Eliminates carcinogen - acids
- Retards oxidative stress
- Prevents wasting dis-ease
- Eases side effects of chemotherapy and radiotherapy
3) Pulmonary
Glutathione is the most efficient free radical (acid) scavenger in the airways,
and dozens of studies have confirmed that free radical (acid) damage is a
primary player in Chronic Obstructive Pulmonary Disease. Rahman I, MacNee W.
Oxidative Stress and Regulation of Glutathione in Lung Inflammation. Eur Respir
J. 2000 Sep; 16(3):534-54.
- Breaks up mucus - Rahman I, MacNee W. Oxidative Stress and Regulation of
Glutathione in Lung Inflammation. Eur Respir J. 2000 Sep; 16(3):534-54
- Cystic fibrosis - Glutathione neutralized harmful oxidants introduced into the
lungs or those released by cells. Exotoxins from bacteria can overload the
endobronchial terrain and feed the fires of acidic inflammation. This staggering
burden increases the oxidative sensitivity of the CF lung, resulting in further
injury of lung parenchyma. Data supports evidence of a decrease in the
antioxidant tri-peptide glutathione (Roum JH, Buhl R, McElvaney NG, et al.
Systemic Deficiency of Glutathione in Systic Fibrosis. J Appl Physiol 1993;
75:19-24).
- Asthma
- Chronic bronchitis
- Emphysema - Lamson, David, MD, Grignall, Matthew, ND. The use of Nebulized
Glutathione in the Treatment of Emphysema: A Case Report. Altern Med Review.
5(5);429-431, 2000 Oct.
- Pulmonary fibrosis - Ishii T, Fujishiro M, Nakajima J, Teramoto S, Ouchi Y,
Matsuse T. Depletion of Glutathione S-Transferase P1 Induces Apoptosis in Huamn
Lung Fibroblasts. Exp Lung Res. 29(7);523-36, 2003 Oct-Nov.
4) Aging
Glutathione is critically important to our brain as it is one of the most
important brain antioxidants. Glutathione helps preserve brain tissue by
preventing damage from free radicals (acids).
In addition to quenching dangerous acids, glutathione also acts to recycle
vitamin E which also has the ability to reduce acidity in the brain. (Perlmutter
D., BrainRecovery.com July 2004, 5th ed:13)
- Autism - Medical literature documents that an out-fection can lead to a
lowering of glutathione which participates in detoxification, interacts with
metallothioneins, and supports many crucial aspects of immunity. A link between
glutathione and autism regression may derive from the fact that transient or
chronic intestinal problems can impair an infant s or toddler s nutritional
status, thereby minimizing the levels of amino-acids required for the production
of glutathione (McCandless, J. Children With Starving Brains. 2003, 2nd ed; 252)
- Parkinson s Disease - Glutathione helps to preserve brain tissue by preventing
damage from free radicals (acids) and destructive chemicals formed by the normal
processes of metabolism, toxic elements in the environment, and as a normal
response of the body to challenges by acidic agents or other stresses. With the
understanding that glutathione is important for brain protection and that this
protection many be lacking in the brains of Parkinson s clients due to
glutathione deficiency, it can be seen as very beneficial. (Di Monte DA, Cahn P,
Sandy MS. Glutathione in Parkinson s Disease: A Link Between Oxidative Stress
and Mitochondrial Damage? An Neurol. 32 Suppl; S111-115, 1992.)
- Alzheimer s Dis-ease - Woltjer, R.L., Hgheim W., Maezawa I., Vaisar T, Montine
K.S., Montine T.J., Role of Glutathione in Intracellular Amyloid-Alpha Recursor
Protein/Carboxy- Terminal Fragment Aggregation and Associated Cytotoxicity. J
Neurochem. 2005 May; 93 (4): 1047-56.
- Huntington s Dis-Ease - Choo Y.S., Mao Z, Johnson GV, Lesort M. Increased
Glutathione Levels In Cortical Striatal Mitochondria of the R6/2 Huntington s
Disease Mouse Model. Neuroscience Letter. 2005 Sep 23; 386(1): 63-8.
- Multiple Sclerosis - Calabrese V, Scapaginini G, Ravagna A, Bella R,
Butterfield DA, Calvani M, Pennisi G, Giuffrida Stella AM. Disruption of Thiol
Homeostasis and Nitrostative Stress in the Cerebrospinal Fluid of Patients with
Active Multiple Sclerosis: Evidence for a Protective Role of Acetylcarnitine.
2003 Sep; 28(9): 1321-8. Mann CL, Davies MB, Aldersea J, Fryer AA, Jones PK, Ko
Ko C, Young C, Strange RC, Hawkins CP. Glutathione S-Transferase Polymorphisms
in MS: Their Relationship to Disability. Neurology. 2000 Feb 8;54(3):542-7.
- ALS - Tohgi H, Abe T, Yamazaki K, Murata T, Ishizake E, Isobe C. Increase in
Oxidized Products and Reduction in Oxidized Glutathione in Cerborospinal Fluid
From Patients with Sporadic Form of Amyotrophic Lateral Sclerosis. Neurosci Lett.
1999 Feb 5; 260(3):204-6.
- Cataract formation
- Macular degeneration
- Cancers of aging
- Prostate problems
- Osteoarthritis - Hammarqvist F, Luo JL, cotgreave IA, Andersson K, Wernerman
J. Skeletal Muscle Glutathione is Depleted In Critically Ill Patients. Crit Care
Med. 25(1):78-84 1997 Jan.
5) Digestive
- Inflammatory bowel dis-ease
- Hepatitis
- Malnutrition
- Pancreatitis
- Peptic ulcer
6) Toxicology
- Detoxifies certain drug overdoses - Acetaminophen has been shown to reduce
glutathione production, thus paving the way for enhanced brain destruction by
metabolic acids. (Perlmutter D. July 2004, 5th ed:108)
- Detoxifies substances in cigarette smoke and auto exhaust - Rahman I, MacNee
W. Lung Glutathione and Oxidative Stress: Implications In Cigarette
Smoke-Induced Airway Disease. Am J Physiol. 277(6 Pt 1);1067-88, 1999 Dec.
- Detoxifies pollutants including heavy metals and pesticides - Elevated
glutathione levels have been shown to protect tissue form lipid peroxidation
created by exposure to certain metals. Consider infusions of glutathione to
relieve the body burden of both neurotoxins and metal toxicity, including
mercury. (Foster, JS. Kane PC, Speight N. The Detoxx Book. 2002;90)
- Prevents hearing loss from noise pollution
- Detoxifies many well-known carcinogens
7) Immunology
- Anti-viral for AIDS, hepatitis, herpes, etc. - Low glutathione levels in HIV
clients may contribute to their immune deficiency since glutathione plays an
important role in the function of lymphocytes. Some lymphocytes require adequate
levels of glutathione in order to function normally, and HIV induces oxidative
stress that depletes the cells of glutathione. Townsend DM, Tew KD, Tapero H.
The Importance of Glutathione in Human Disease. Biomed Pharmacother. 2003
May-June;57(3-4):145-55. Droge W, Holm E. Role of Cysteine and Glutathione in
HIV Infection and other Diseases Associated with Muscle Wasting and
Immunological Dysfunction. FASEB J, 11(13):1077-89 1997 Nov.
- Lyme Dis-Ease - Lyme dis-ease is a seriously complex multi-system acidic
inflammatory condition that is triggered by bacterial exotoxins. Glutathione
helps to remove exotoxic and/or mycotoxic acids by forming a soluble compound
with them, which can then be excreted through the urine or gut. (Can Glutathione
Help Lyme Disease Sufferers? Excerpt from: The Glutathione Report: Optimal
Health with the Master Antioxidant, Issue 4, Volume 1, May 2004).
- Natural antibiotic
- Chronic fatigue syndrome - An article in the journal of Medical Hypothesis
proposed that glutathione, an antioxidant essential for lymphocyte function, may
be depleted in Chronic Fatigue Syndrome patients. Glutathione is needed for both
the immune system and for aerobic muscular contraction. The authors proposed
that glutathione depletion by an activated immune system also causes the
muscular fatigue and myalgia associated with Chronic Fatigue Syndrome (Bounous
et al. 1999).
8) Metabolic
- Athletic enhancement
- Decreases recovery time from physical stress
- Supports hemoglobin in kidney failure -
Diabetes - The blood and tissues of diabetics are marked by critically low
glutathione levels. Glutathione depletion may have adverse consequences in
diabetic clients independent of glycemic control, and it may weaken the defense
against oxidative stress. De Mattia G, Bravi MC, Laurenti O, Cassone-Faldetta M,
Armiento A, Ferri C, Falsano F. Influence of Reduced Glutathione Infusion on
Glucose Metabolism in Patients with Non-insulin Dependent Diabetes Mellitus.
Metabolism. 1998 Aug;47(8):433-8.
Glutathione provides the body with tools to fight off these threats naturally.
Healthy people also benefit from elevated glutathione levels through an enhanced
ability to fight off acidic toxins, dis-ease, pre-cancerous cells and the aging
process itself. Diminished glutathione levels are a symptom of aging and are
particularly evident in such aliments as Parkinson s dis-ease and Alzheimer s
dis-ease.
Glutathione is also important to physically active people. Many world-class
athletes are discovering that well-maintained glutathione levels gives them the
edge over their competitors, bringing greater strength and endurance, decreased
recovery time from injury, less muscle pain and fatigue, and muscle-promoting
activity.
Putting It All Together
1) Medical science is still ascertaining all the critical roles played by
glutathione in dis-ease resistance and general good health. Clinical evidence
links low glutathione levels to the most common illnesses of our time as well as
newly emerging dis-eases.
2) As an essential aid to health, glutathione works as the master antioxidant in
our body, optimizes the white blood cells and detoxifies a long list of
pollutants and carcinogens or acids. The best way to raise glutathione levels is
by eating foods that are high in glutathione such as avocados.
This is why I created the first natural water-based oral glutathione from
avocados.
To order the World s first Liquid Glutathione, choose below:
Buy Three Get One FREE (4 oz.)
Buy Three Get One FREE (2 oz.)
3) Pharmaceutical medicine has created drugs that do this very effectively. They
have their uses in critical situations. But they also have side effects and
repeated use is clearly inadvisable.
Recently, I have developed a natural way to raise glutathione levels by safe,
reliable dietary means. The emergence of bioactive avocado glutathione is an
exciting step forward in non-nutritive supplementation.
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References:
Aging
It is well known that aging is accompanied by a precipitous fall in glutathione
levels. Lower glutathione levels are implicated in many dis-eases associated
with aging including cataracts, Alzheimer s, Parkinson s atherosclerosis and
others.
Journal of Clinical Epidemiology 47:1021-26, 1994.
Antioxidant Functions
Antioxidants are well documented and known to play vital roles in health
maintenance and dis-ease prevention. Glutathione is your cell s own major
antioxidant. Maintaining elevated glutathione levels aids the body s natural
antioxidant function.
Biochemical Pharmacology 47: 2114-2123, 1994.
Neurological Dis-ease
Low glutathione levels have been associated with nuero-degenerative dis-eases
such as MS (Multiple Sclerosis), ALS (Lou Gehrig s Dis-ease), Alzheimer s and
Parkinson s.
The Lancet 344: 796-798, 1994.
Cancer
Glutathione plays a role in eliminating many carcinogens/acids and also
maintains and optimizes white blood cell function while providing stronger
anti-acidic/anti-tumor defenses.
Cancer Letters 57: 91-94, 1991.
Athletic Performance
Raised glutathione levels help increase strength and endurance. Those interested
in physical fitness can benefit from a definite athletic edge.
Journal of Applied Physiology 87: 1381-1385, 1999.
Toxins, Pollution and Radiation
Glutathione detoxifies a variety of pollutants, carcinogens and poisons
including many found in fuel exhaust and cigarette smoke. It also retards damage
from radiation exposure due to the eroding ozone layer.
Annual Reviews of Biochemistry 52: 711-760, 1983
AIDS
Glutathione levels correspond to poor survival of AIDS patients. Much
documentation demonstrates the role of enhanced glutathione levels in AIDS.
Proceedings of the National Academy of Science, USA 94: 1967-72, 1997.
Heart Dis-Ease, Stroke and Cholesterol
Raised glutathione levels fight the oxidation of fats circulating in the
bloodstream including cholesterol, retarding the process of plaque formation in
the arteries leading to most heart attacks and strokes.
Nutrition Reviews 54: 1-30, 1996.
Diabetes
Diabetics are more prone to out-fections and circulatory problems leading to
heart dis-ease, kidney failure and blindness. Glutathione protects against the
complications of diabetes.
Clinical Science 91:575-582, 1996
Lung Dis-Ease
Doctors have used glutathione-promoting drugs to treat many lung diseases
including asthma, chronic bronchitis and emphysema New and potentially
therapeutic roles can be found for cigarette smoke damage, pulmonary fibrosis
and other illnesses.
American Journal of Medical Science 307:119-127, 1994
Digestive Disorders
Glutathione protects the body from inflammation of gastritis, stomach ulcers,
pancreatitis and inflammatory bowel dis-ease including ulcerative colitis and
Crohn s dis-ease.
Gut 42: 485-492, 1998
Hepatitis
The liver is a major storehouse for glutathione. Glutathione is impaired in
alcohol hepatitis as well as in viral (acidic) hepatitis including hepatitis A,
B, and C. Raised glutathione levels help restore liver function.
American Journal of gastroenterology 91: 2569-2573, 1996
Kidney Dis-Ease
Those with kidney failure or on dialysis suffer from high levels of oxidative
(acidic) stress and decreased glutathione levels. Raised glutathione levels help
prevent anemia.
Nephron 61: 404-408, 1992
Pregnancy, Lactation and Childbirth
Glutathione s role in fetal and placental development is critical. It also acts
in the placenta to detoxify pollutants before they can reach the developing
child. Many complications of pregnancy have been linked with poor glutathione
levels.
Early Human Development 37: 167-174, 1994
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